摘要
目的探讨笑气吸入镇痛和自控硬膜外镇痛的镇痛效果以及对产妇和新生儿的影响。方法选择200例产妇分为观察组和对照组;观察组于活跃期给予吸入含50%氧化亚氮和50%氧气的混合气体;对照组于产程活跃期给予硬膜外麻醉,接自控镇痛泵联合注入罗哌卡因和芬太尼;分别观察两组产妇的镇痛效果、产程时间、分娩方式、血氧饱和度及新生儿脐动脉血的血气分析、新生儿窒息情况。结果在镇痛效果方面,观察组镇痛分级Ⅰ级为50例,Ⅱ级为35例,对照组0级为76例,Ⅰ级为18例;两组比较有显著性差异(P<0.01)。产程时间、新生儿窒息率、血气分析结果比较均无显著性差异(P>0.05)。结论笑气吸入用于分娩镇痛安全有效,易被产妇接受,值得临床推广应用;自控硬膜外镇痛用于分娩镇痛效果满意,对产妇及新生儿无明显副作用,可作为分娩镇痛的首选方法。
Objective To explore the effect of inhalation of nitrous oxide and patient controlled epidural analgesia（PCEA） on relief of pain in delivery and the influence on mother and infants. Methods Two hundreds pregnant women were divided into investigation group （100 cases） and health control group（ 100 cases）; inhalation of nitrous oxide premixed with oxygen（50% ： 50% ） was given in investigation group. Epidural analgesia was given to pregnant women at the active stage of labor by injecting ropivacaine and fentanyl with patient-control instrument in health control group. Observation was made on the effective outcome of different analgesia, duration of labor, way of delivery, oxygen saturation of blood, blood gas analysis of umbilical artery of newborn and neonatal asphyxia. Results Regarding grading of the effective analgesic outcome,grade I in 50 cases and grade II in 35 cases in investigation group;grade zero was found in 76 cases and grade I in 18 cases in health control group. There was significant difference in the comparison of analgesia among the 2 groups（P〈 0.01 ） and no significant difference was found in the comparison of duration of labor, blood gas analysis of umbilical artery of newborn and the rate of neonatal asphyxia （P 〉0.05）. Conclusion Inhalation of nitrous oxide is safe and effective,it is acceptable,which is worthy of clinically popularizing in obstetrics. PCEA is one of optimal analgesia on relief of pain in delivery,with less side-effect,it can be taken as the first choice.
出处
《中国现代医生》
2009年第10期32-33,57,共3页
China Modern Doctor
关键词
镇痛
分娩
硬膜外
笑气
Analgesia
Delivery
Epidural
Nitrous oxide
