摘要
Immunocytochemical localization of 5-hydroxytryptamine (5-HT) containing cells of the guinea-pig pancreas was studied by means of PAP-glucose oxidase-DAB-nickel (PAP-GDN) and PAPstaining methods on paraffin sections. In this study we demonstrated the presence of 5-HTimmunoreactive cells in the endocrine (islets) and exocrine pancreas of the guinea-ping. Cells exhib-iting 54-HT immunoreactivity were found in the center and the periphery of the pancreatic islets. The5-HT immunoreactive granules were evenly distributed throughout the cytoplasm, but was faint inthe nuclei. Cells of this type were also distributed in the exocrine pancreas. Grouped or single or single cellsoccurred intercalatedly between acinar cells, as well as in the epithlium of ducts and in the connectivetissues near the ducts or acini.
Immunocytochemical localization of 5-hydroxytryptamine (5-HT) containing cells of the guinea- pig pancreas was studied by means of PAP-glucose oxidase-DAB-nickel (PAP-GDN) and PAP staining methods on paraffin sections. In this study we demonstrated the presence of 5-HT immunoreactive cells in the endocrine (islets) and exocrine pancreas of the guinea-ping. Cells exhib- iting 54-HT immunoreactivity were found in the center and the periphery of the pancreatic islets. The 5-HT immunoreactive granules were evenly distributed throughout the cytoplasm, but was faint in the nuclei. Cells of this type were also distributed in the exocrine pancreas. Grouped or single or single cells occurred intercalatedly between acinar cells, as well as in the epithlium of ducts and in the connective tissues near the ducts or acini.
