摘要
本文对11例难辨梭菌性肠炎(CDEC)患者的粪便进行10种肠道菌的定量分析,并与20例其他原因腹泻病人和22例健康成人的肠菌比较。结果表明CDEC病人的粪中大肠杆菌和双歧杆菌明显低于两对照组,其他菌类与对照组无明显差别,提示大肠杆菌和双歧杆菌的减少在CDEC发病中起重要作用。此外,我们对CDEC病人发病前所用抗生素作了统计分析,结果发现:使用较多的有庆大霉素。
A total of 11 faecal specimens of Clostridium difficile-associated colitis (CDEC) were analysed for the contents of 10 microflora, and the results were compared with the flora of 20 cases with different causes other than CDEC diarrheal patients (casecontroll)and 22 health adults(health-controll)during April 1988 to March 1989. The results showed that the numbers of E. coli and Bifidobacteria in CDEC patients were found lower tban those in controlls, suggesting that the decrease of these two bacteria played an important role in the development of CDEC. The numbers of other bacteria were close to those in controlls. Moreover, we analysed the frequency of various antihiotics used in CDEC patients. The antibiotics at risk have been found to be ampicillin, cephalosporin and gentamycin.
出处
《中国微生态学杂志》
CAS
CSCD
1989年第1期69-71,共3页
Chinese Journal of Microecology
关键词
难辨梭菌
肠菌群
抗生素
Clostridium difficile Intestinal microflora Antibiotic