摘要
β—血小板球蛋白(β—TG)是由血小板α——颗粒释放出来的一种特异性蛋白质。迄今,对于它是否抑制血管内皮细胞生成前列环素(PGI_2)这一问题尚无定论。本文应用本室纯化的β—TG进行实验,结果未能证实它对牛和猪主动脉内皮细胞生成PGI_2有任何影响。同时,在本实验条件下也尚未证实牛主动脉内皮细胞上β—TG特异结合部位的存在。
β-thromboglobulin (β-TG) is a platelet-specific protein which is released by platelet a-granules. To this day, no final conclusion has yet been reached on whether β-TG inhibits PG I_2 production by vascular endothelial cells (VEC). In the thesis, human β-TG which is purified by our own department is used,and any effects of β-TG on PG I_2 production by bovine and porcine aortic endothelial cells are not verified. In addition, under our department β-TG specific binding sites on bovine aortic endothelial cells are not found.
出处
《中南医学科学杂志》
CAS
1989年第2期115-118,230,共5页
Medical Science Journal of Central South China
