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Fast cleavage of 3', 5'-cycIic adenosine monophosphate and 3', 5'-cyclic guanosine monophosphate by lanthanides

Fast cleavage of 3', 5'-cycIic adenosine monophosphate and 3', 5'-cyclic guanosine monophosphate by lanthanides
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摘要 Synthetic nucleases which rapidly cleave nucleic acids under mild conditions have many important potential applications ranging from the synthesis of custom-designed artificial restriction enzymes to the development of new antitumor drugs. Nonenzymatic hydrolysis of nucleic acids has been attracting increasing interest. However, the cleavage of nucleic acids by lanthanides has rarely been reported, and only Sumaoka et al. observed
出处 《Chinese Science Bulletin》 SCIE EI CAS 1995年第24期2044-2048,共5页
基金 the National Program "The Basic Research of Rare Earth Science" of China and the Fundamental Bureau of Chinese Academy of Sciences.
关键词 LANTHANIDES CAMP CGMP cleavage. lanthanides, cAMP, cGMP, cleavage.
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