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Capillary Electrophoretic Separation of Monosialogangliosides by using cyclodextrin and borax as selectors

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摘要 f The CE separation of monosialogangliosids (MSGLS) is generally difficult owing to theirmixed micelle formation. The addition of high concentration of borax to the buffer containing α-Cyclodextrin allowed for improvement of selectivity of separation. Under the optimum conditions,several forms of MSGLS were successfully separated and the commercial standard GM1 gave twopeaks, suggesting that the standard may contain two different types of species. f The CE separation of monosialogangliosids (MSGLS) is generally difficult owing to theirmixed micelle formation. The addition of high concentration of borax to the buffer containing α-Cyclodextrin allowed for improvement of selectivity of separation. Under the optimum conditions,several forms of MSGLS were successfully separated and the commercial standard GM1 gave twopeaks, suggesting that the standard may contain two different types of species.
机构地区 CHINESE ACAD SCI
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 1996年第11期1033-1034,共2页 中国化学快报(英文版)
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