摘要
目的：为了解本地区支扩感染加重需住院患者的病原学及药敏情况，指导临床治疗。方法：用纤支镜取深部痰作培养和药敏以及血清ＩｇＧ测定。结果：７４例深部痰培养６０例阳性，阳性率为８１．１％，最常见的病原菌为假单孢菌属； ７２例患者有 ５３例 ＩｇＧ降低，平均值为 ６． ５±１． ２ｇ／Ｌ。结果：患者免疫功能低下和革兰氏阴性杆菌特别是铜绿假单抱杆菌感染是引起支扩感染加重住院的主要因素。在抗菌药物应用时宜选用对假单孢菌有效的药物。
Objectives: To investigate the etiology and drug sensitivity in the native patients with bronchi- ectasis complicated with severe infection, so as to provide instruction for clinical application of anti- biotics to this disease. Methods: Sputum in the deep part of the lungs was sampled out by using bronchoscope and cultured for analysis of drug sensitivity and detection of serum IgG. Results: In the test of sputum culture 60 out of 74 samples appeared positive, the positive rate was 81. 61 %. The most frequent pathologic bacterium was pseudomonas. A decrease in serum IgG was observed in 53 out of 72 patients, the average level was 6. 5 ±1. 2g/L. Conclusion: The main factors that in- duce severe infection in bronchiectasis were the lowered immune function in the patients and the infection of Gram-negative bacteria, especially blue verditer pseudomonas. Antibiotics effective to pseudomonas are recommended to treat the infection complicated in bronchiectasis.
出处
《广州医学院学报》
1999年第2期44-46,共3页
Academic Journal of Guangzhou Medical College
