A New Rearrangement Reaction of 2-Phenyl Substituted Benzothiazepine with Ethoxycarbonyl Carbene─Mechanism of the Reaction and Structure of the Product

A New Rearrangement Reaction of 2-Phenyl Substituted Benzothiazepine with Ethoxycarbonyl Carbene─Mechanism of the Reaction and Structure of the Product

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摘要 2,3-Dihydro-2-phenyl-4-(4-methoxyphenyl)-1, 5-benzothiazepine reacts with ethoxycarbonyl carbene to give an unexpected compound 2,3-disubstituted-4H-1,4-benzothiazine Ⅲ. It was found to be a new rearrangement reaction and the structure of the product was confirmed by IR, NMR, MS. 2,3-Dihydro-2-phenyl-4-(4-methoxyphenyl)-1, 5-benzothiazepine reacts with ethoxycarbonyl carbene to give an unexpected compound 2,3-disubstituted-4H-1,4-benzothiazine Ⅲ. It was found to be a new rearrangement reaction and the structure of the product was confirmed by IR, NMR, MS.

作者 Hong Zhong WANG Dan YAO Ruo Xi LAN Jia Xi XU Sheng JIN (College of Chemistry and Molecular Engineering, Peking University, Beijing 100871)

出处《Chinese Chemical Letters》 SCIE CAS CSCD 1999年第8期625-628,共4页 中国化学快报（英文版）

关键词 BENZOTHIAZEPINE ethoxycarbonyl carbene rearrangement reaction Benzothiazepine, ethoxycarbonyl carbene, rearrangement reaction

分类号 O621 [理学—有机化学]

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Chinese Chemical Letters

1999年第8期

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A New Rearrangement Reaction of 2-Phenyl Substituted Benzothiazepine with Ethoxycarbonyl Carbene─Mechanism of the Reaction and Structure of the Product

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