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NEUROGENIC INFLAMMATION EVOKED BY STIMULATION OF THE ACUPOINT THROUGH DRR

NEUROGENIC INFLAMMATION EVOKED BY STIMULATION OF THE ACUPOINT THROUGH DRR
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摘要 The purpose of this study is to investigate whether stimulation of the acupoint evoked the neurogenic inflammation distributed along the meridian through DRR (dorsal root reflex). We used 11 rats whose ventral roots below L 1 were cut off and the spinal cords were transected between T 13 and L 1. After intravenous injection of Evans blue liquid and continuous electrostimulation of the right Chengshan acupoint of the rat, Evans blue extravasation distributed along the Bladder Meridian of Foot Taiyang was observed on the skin of lower back and both hindlimbs. By means of measuring the amount of Evans blue, it was shown that the amount of Evans blue spot in the skin with the extravasation was obviously different from that in the skin of 1 0 mm apart from (P<0 01), also obviously different from that in the skin of the upper back and from that in the skin of the control group (P<0 01), also whown that the amount of Evans blue in the bladder, ureter and germen was obviously different from that in the control group (P<0 01). These results indicate that the stimulation of the acupoint may produce the neurogenic inflammation of ipsilateral and contralateral skin up to several adjacent spinal segments as well as may produce the neurogenic inflammation of ipsilateral and contralateral visceral organs related to the Bladder Meridian through DRRs. The purpose of this study is to investigate whether stimulation of the acupoint evoked the neurogenic inflammation distributed along the meridian through DRR (dorsal root reflex). We used 11 rats whose ventral roots below L 1 were cut off and the spinal cords were transected between T 13 and L 1. After intravenous injection of Evans blue liquid and continuous electrostimulation of the right Chengshan acupoint of the rat, Evans blue extravasation distributed along the Bladder Meridian of Foot Taiyang was observed on the skin of lower back and both hindlimbs. By means of measuring the amount of Evans blue, it was shown that the amount of Evans blue spot in the skin with the extravasation was obviously different from that in the skin of 1 0 mm apart from (P<0 01), also obviously different from that in the skin of the upper back and from that in the skin of the control group (P<0 01), also whown that the amount of Evans blue in the bladder, ureter and germen was obviously different from that in the control group (P<0 01). These results indicate that the stimulation of the acupoint may produce the neurogenic inflammation of ipsilateral and contralateral skin up to several adjacent spinal segments as well as may produce the neurogenic inflammation of ipsilateral and contralateral visceral organs related to the Bladder Meridian through DRRs.
出处 《Journal of Pharmaceutical Analysis》 CAS 1999年第2期175-175,共1页 药物分析学报(英文版)
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