摘要
目的总结上消化道大出血患者应用脑垂体后叶素致严重低钠血症的临床经验。方法收集湖北省部州市中心医院消化内科1999年6月至2004年12月收治的2460例上消化道大出血应用脑垂体后叶素治疗的患者的病例资料,观察消化道症状及神经、精神等全身症状及动态监测血钠监测结果。结果其中30例发生严重低钠血症,发生率为1.22%。血清钠<110 mmol/L。临床表现为恶心、呕吐、昏睡、昏迷、抽搐等。治疗采取补充高浓度钠,停用垂体后叶素,含盐饮食,动态监测血清钠浓度。所有患者均在治疗后1～3 d 好转,无一例死亡。结论上消化道大出血患者应用脑垂体后叶素治疗过程中易出现严重低钠血症,应严密观察患者临床表现,及时监测血钠,一旦发生低钠血症及时治疗。
Objective To summarize the clinical experience of serious hyponatremia resulted from applying pitnitrin to massive hemorrhage of gastrointestinal tract patients.Methods we used pitritrion on 2460 such patients and examined some symptoms of the digestive tract and nerve system,monitoring the dynamic state of blood sodium.Results The re- suits reveal that patients in 30 cases turned out to suffer from serious hyponatremia,whese sodium in the serum appeared less than 110 mmol/L,which was 1.22% of the rest subjects'.The relevant symptoms included nausea,vomit,spoor,coma and twitch etc.Following remedies included liquid supply with a high-concentrated sodium,ceasing using pituitrin,in- take of salute foods,and dynamic monitoring on the state of sodium in the serum.All patients recovered in 1 to 3 days without a single failure.Conclusion Thus we reach this conclusion:When applying pituitrin to massive hemorrhage of gastrointestinal tract patients,the above mentioned symptoms should be closely examined,and blood sodium should be timely monitored so that proper treatment should arrive in time.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2007年第S1期202-203,共2页
Chinese Journal of Practical Internal Medicine
