摘要
天津市武清区人民医院病理研究室天津市 301700
Objective: To explore the clinical and pathological characteristics of gastrointestinal carcinoid tumors (GICT) and to investigate methods for diagnosing GICT. Methods: The clinical materials of 53 cases of GICT seen in Wuqing People's Hospital and Cancer Institute and Hospital of Tianjin Medical University between January 1995 and December 2006 were retrospectively analyzed. Results: Of the 53 cases, 18 cases had tumor lesions in the appendix, 12 cases had lesions in the rectum, 8 cases had lesions in the colon, 7 cases had lesions in the stomach, 5 cases had lesions in the small intestine, and 3 cases had lesions in the duodenum. All of the patients were treated with surgical excision and the diagnosis was confirmed by endoscopic biopsy or surgery. Of the 53 cases, 28 cases were diagnosed by endoscopic biopsy before surgery. Eight cases presented with carcinoid syndrome, and 18 cases died of metastases. The main clinical manifestations of patients were stomachache in 40 cases (75.5%), sensation of fullness after eating in 4 cases (7.5%), changes in defecation habits in 15 cases (28.3%), emaciation in 12 cases (22.6%), mucopurulent bloody stool in 7 cases (13.2%), incomplete intestinal obstruction in 8 cases (15.1%), abdominal mass in 10 cases (18.9%) and carcinoid syndrome in 8 cases (15.1%). There were three types of GICT: typical, atypical and parvicellular. Conclusion: The diagnosis of GICT mainly depends on pathological detection and immunohistochemistry. Tumor size, differentiation, infiltration, local lymph node invasion, and metastasis are correlated to prognosis. Surgery is the best choice for the treatment of GICT.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2009年第7期372-374,共3页
Chinese Journal of Clinical Oncology
关键词
胃肠道
肿瘤
类癌
病理学
Gastrointestinal tract
Neoplasm
Carcinoid tumor
Pathology