摘要
目的分析嗜酸细胞胃肠炎(EG)的临床特点,诊断要点和治疗预后及其误诊原因。方法对8例EG患者的既往史,病史,临床表现,实验室检查,内镜表现,骨髓细胞学检查及治疗情况进行分析。结果黏膜型患者以腹痛,腹泻为主要表现,肌层型以肠梗阻为主要表现伴有腹胀,恶心和呕吐,浆膜型以腹胀,腹水为主要症状,有时伴有低热,腹水中可见大量嗜酸细胞浸润,内镜无特异性表现,表现为浅表性胃炎,糜烂性胃炎,十二指肠球炎,回肠末端炎症,全结肠溃疡性改变,活检大部分组织有大量嗜酸细胞嗜酸细胞浸润,激素治疗可在1周内明显缓解,嗜酸细胞逐渐恢复正常。结论 EG临床和内镜表现无特异性,外周血嗜酸细胞,尤其是胃肠黏膜组织中嗜酸细胞增多是诊断的重要依据。
Objective To investigate clinicai presentation,diagnosis and prognosis of eosinophilic gastroenteritis(EG),and analyze causes of misdiagnosis.Methods Eight patients diagnosed as EG were studied.Theirh istory,clinical manifestations,laboratory tests,endoscopies and Bone Marrow Examination and follow-up data were analyzed.Results The patients with mucosal type usually had abdominal pain,sometimes with possible diarrhea.Bowel obstruction occurred generally in patients diagnosed as muscular type with bloating,nausea,vomiting.Bloating,ascites occured predominantly in those with serosal type,Probably accompanied by low fever and eosinophilic infiltration in ascites.Endoscopy showed characterlessly superficial gastritis,erosive gastritis,duodenitis,Inflammation of the end of ileum,an ulcer of total colon,Eosinophilia infiltration in mucosa was confimed by biopsy.Glucocorticoid therapy could relieve symptoms and eosinophlia.Symptom probably recurred byg ood prognosis.Conclusion Clinical and endosopic presentation are not specific,therefore the presence of enosinphilia in peripherai blood,especially in gastrointestinal mucosa strongly indicate the diagnisis evidence of important.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2010年第S1期47-49,共3页
Chinese Journal of Practical Internal Medicine
关键词
嗜酸细胞胃肠炎
嗜酸细胞
临床表现
eosinophilic gastroenteritis
eosinocyte
clinical manifestations
