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水源性蓝氏贾第鞭毛虫分子生物学检测方法研究进展

Research progress on the molecular detection of waterborne Giardia lamblia
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摘要 蓝氏贾第鞭毛虫具有一系列适丁水源性传播的生物学特征,广泛存在于污水、原水、处理水等水体中,严重威胁公共卫生安全。水源性贾第虫的检测主要是通过免疫磁珠分离后进行分子鉴别。运用单个基因作为分子标志的检测方法的可靠性值得商榷,而全基因组扩增技术和DNA微阵列技术具有重要的应用前景。 Giardia lamblia is waterborne transmission facilitated by a series of its biological traits. It exists in sewage water, raw water, treated water and other water systems extensively as a serious public heahhthreatening pathogen. Waterborne Giardia is mainly identified by molecular methods after immunomagnetic separation. It is not reliable to use a single gene as molecular marker to detect this pathogen. Instead, whole gehome amplification and DNA microarray are promising methods.
出处 《国际医学寄生虫病杂志》 CAS 2009年第2期114-117,共4页 International JOurnal of Medical Parasitic Diseases
关键词 蓝氏贾第鞭毛虫 检测 全基因组扩增 DNA微阵列 减数分裂重组 Giardia lamblia Detection Whole genome amplification DNA microarray Meiotic recombination
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参考文献25

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