摘要
【目的】分析影响肺癌预后各种因素，为肺癌的防治提供科学依据。【方法】对湖南省肿瘤医院胸外科2003年1月至2004年1月期间具有明确病理学类型和临床分期的226例肺癌手术病例，经查阅病历并随访，回顾性分析、比较影响肺癌患者生存预后的因素。【结果】共随访226患者，失访18人，有效病例208例；随访率92％。采用Cox单因素及多因素分析，对12个协变量进行统计学处理表明：肿瘤家族史、临床分期、原发肿瘤大小、淋巴结转移、辅助化或（和）放疗影响肺癌手术患者预后。【结论】肿瘤家族史、临床分期、原发肿瘤大小、淋巴结转移、辅助化或（和）放疗是独立的影响肺癌手术患者预后的因素。
[Objective] To analyze the prognostic factors of lung cancer and to find some clues for prevention and clinical treatment of tung cancer in the future. [Methods] The data of 226 hospitalized patients with lung cancer after surgery in Thoracic Surgery of Hunan Tumor Hospital from January 2003 to January 2004 were reviewed and followed up. The factors which might impact on the prognosis of patients were analyzed including general information of the patients themselves,the tumor data and different treatment manners. [Resuits] A total of 226 cases were involved in this study and 208 of them were followed up to the end-point of the study with 8 % （18 cases） of loss to follow-up. Cox regression indicated that family tumor history,tumor clinical stage, primary tumor size, lymph node metastasis and adjuvant therapy were independent prognostic factors of patients with lung cancer. [Conclusion] family tumor history,tumor clinic stage,primary tumor size,lymph node metastasis and adjuvant therapy are independent prognostic factors of lung cancer patients after surgery.
出处
《医学临床研究》
CAS
2009年第3期461-463,共3页
Journal of Clinical Research
