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肾移植术后早期排异的处理

Management of Early Postoperative Renal Transplant Rejection
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摘要 目的:探讨肾移植早期急性排斥反应的诊断及治疗方法。方法:肾移植98例病例中对18例肾移植术后发生早期(1个月内)急性排斥反应的诊断及治疗进行分析。结果:18例早期急性排斥反应经治疗后均成功。结论:早期急性排斥反应是同种异体肾移植术后最重要问题之一,甲强龙能很好的使术后早期急性排斥反应逆转。对加强龙反应差者,及时配合应用FK506,抗CD3可使术后早期急性排斥反应逆转。成功的关键是早期诊断,早期治疗。 Objective: To investigate the diagnosis and treatment of early acute rejection after renal transplantation. Method: The diagnosis and treatment of 18 in 98 patients who suffered from acute rejection within 1 month after renal transplantation were analyzed. Result: All the 18 patients received successful treatment. Conclusion: The early acute rejection after renal transplantation is one of the most important issue. Prednisolone can make a good reversal. To poor- response cases to the prednisolone, the application of FK506, anti -CD3 in time can well reverse the early postoperative acute rejection. The key step to success is early diagnosis and treatment.
出处 《河北医学》 CAS 2009年第3期280-282,共3页 Hebei Medicine
关键词 肾移植 急性排异反应 Renal transplantation Acute rejection
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  • 1Mulloy LL, Wright F, Hall ML, Moore M. Simulect(basiliximab) reduces acute cellular rejection in renal allografts from cadaveric and living donors [ J ]. Transplant Proc, 1999,31 ( 1 - 2) :1210 - 1213. 被引量:1
  • 2唐孝达.急性排斥反应的诊断与治疗[J].新医学,1999,30(3):132-133. 被引量:4
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  • 4Kamath S, Dean D, Peddi VR, Schroeder TJ etc. Efficacy of OKT3 as primary therapy for histologically confirmed acute renal allograft rejection [ J ]. Transplantation, 1997,64 (10) : 1428 - 1432. 被引量:1

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