摘要
为了探讨连续反应时间（CRT）测定诊断亚临床肝性脑病的意义，我们用自行研制的CRT-I型微电脑测试仪检测了60例正常人和102例不同临床类型肝病病人的CRT。结果正常人对声信号和光信号刺激CRT的P10、P50、P90、P50／（P90－P10）正常值估计分别为234．3ms、264．4ms、318．0ms和1．7560及264．4ms、323．3ms、427．6ms和1．4521。慢性重型肝炎和肝硬化病人对声和光信号刺激的CRT的P10、P50和P90均较正常对照明显延长（P＜0．01，而P50／（P90－P10）比值较正常对照明显减少（P＜0．05和0．01）；各组病例对声刺激比光刺激敏感。55％的慢性重型肝炎病人和80％肝硬化在出现临床型肝性脑病前CRT延长。初步结果显示CRT测试对亚临床型肝性脑病有一定诊断价值。
In order to study the diagnostic significance for subclinical hepatic encephalopathy (SHE) continuous reaction times(CRT),in 102 cases with various clinical type liver diseases and 60 normal controls CRT were measured by means of CRT-1 type Ancrocomputerized meter which researched and tnade by ourselves. The results were as follows:the P10,P50,P90 and P50/(P90-P10) of CRT to sound and light stimulations in normal controis were 234. 3ms and 246. 4ms, 246. 4ms and 323. 3ms, 318. 0ms and 427. 6me, 1. 7560 and 1. 4521,respectively;theP10, P50 and P90 of CRT of chronic severe hepatitis and cirrhosis Patients reacting to both stimulations were significantly prolonged than normal controls (P＜0.01),but the P50/(P90-P10) were significantly decreased than normal controls (P＜0.05 and 0.01). Sound stimulation was more sensitive than light stimulation. About more than 55％ of chronic severe hepatitis and 80％ of cirrhosis Patients had CRT prolonged before presenting clinical encephalopathg;but the CRT abnormal rates of chronic and acute hepatitis Patients were very lower. These results suggest CRT measurement may hare some diagnostic value to SHE,but its application value needs to be studied further.
出处
《重庆医学》
CAS
CSCD
1998年第3期155-158,共4页
Chongqing medicine
关键词
肝性脑病
诊断
连续反应时间
测定
亚临床型
Continuous reaction times Subclinical hepatic encephalopathy Diagnosis
