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治疗幽门螺杆菌感染相关消化性溃疡疗效分析 被引量:5

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摘要 目的观察口服奥美拉唑和静脉滴注美拉唑的三联疗法对幽门螺杆菌(Hp)相关消化性溃疡的疗效[1],以期寻找更经济、实用治疗方案。方法92例消化性溃疡患者,随机分成两组,治疗组48例,口服奥美拉唑,对照组44例,静脉滴注奥美拉唑,两组均服用阿莫西林及黄连素,疗程为2周,停药4周后复查胃镜。结果治疗组溃疡愈合为44例(92%),对照组为42例(95%);治疗组Hp清除率40例(83%),对照组为38例(86%),两组比较差异均无显著性(P>0.05)。结论两种方案治疗Hp感染相关消化性溃疡的疗效、Hp根除率相近,但口服奥美拉唑费用远低于静滴奥美拉唑,不良反应少,为更经济、实用方案。
作者 李桂娟
出处 《中国现代药物应用》 2009年第7期76-77,共2页 Chinese Journal of Modern Drug Application
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  • 1李德爱,张芳,石杰,陈安进.抗幽门螺杆菌感染的消化性溃疡药物经济学研究[J].中国医刊,2005,40(12):37-38. 被引量:2
  • 2董全江.幽门螺杆菌与胃酸相互作用的生物学及治疗意义[J].国外医学(消化系疾病分册),1996,16(4):211-223. 被引量:6
  • 3Dore MP, Leandro G, Realdi G, et al. Effect of pretreatment antibiotic resistance to metronidazole and clarithromycin on outcome of Helicobacter pylori therapy. Dig Dis Sci, 2000, 45 (1): 68-76. 被引量:1
  • 4Megraud Francis. Epidemiology and mechanism of antibiotic resis tance in helicobacter pylori. Gastroenterology, 1998, 115 (5): 1278 12-82. 被引量:1
  • 5Glupezynski Y. Antimicrobial resistance in Helicobacter pylori: a global overview. Acta Gastroenterol Belg, 1998, 61 (3): 357 366. 被引量:1
  • 6Van Zwet AA, Vandenbrouke Grauls CM, Thijs JC, et al. Stable amoxicillin resistance in Helicobacter pylori. Lancet, 1998, 352 (14): 15-95. 被引量:1
  • 7Banatvala N, Davies GR, Abdi Y, et al. High prevalence of Helicobacter pylori metronidazole resistance in migrant to east London: relation with previous nitroimidazole exposure and gastroduodenal disease. Gut, 1994, 35 (11 12): 1562 15-66. 被引量:1
  • 8Lam SK, Talley NJ. Helicobacter pylori consensus: report of the 1997 Asia Pacific consensus conference on the management of Helicobacter pylori infection. J Gastroenterol Hepatol 1998, 13 (1): 1-12. 被引量:1
  • 9Van Der Wouden EJ, Thijs JC, Van Zwet AA, et al. Nitroimi dazole resistance in Helicobacter pylori. Alimint Pharmacol Ther,2000, 14 (1): 7-14. 被引量:1
  • 10Li Y Y,J Gastroenterol Hepatol,1996年,11卷,增1期,A35页 被引量:1

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  • 1姜正其.雷贝拉唑、呋喃唑酮、阿莫西林三联治疗幽门螺杆菌相关消化性溃疡的临床观察[J].中外医疗,2008,27(22):1-2. 被引量:9
  • 2徐美华,张桂英,李常娟.含铋剂四联一线治疗方案根除幽门螺杆菌疗效观察[J].浙江大学学报(医学版),2011,40(3):327-331. 被引量:31
  • 3陆再英,钟南山.内科学[M].北京:人民卫生出版社,2008:121. 被引量:1688
  • 4Zojaji H, Talaie R, Mirsattari D, Haghazali M, Mo- laei M, Mohsenian N, Derakhshan F, Zali MR. The efficacy of Helicobacter pylori eradication regimen with and without vitamin C supplementation. Dig Liver Dis 2009; 41:644-647 [PMID: 19493713 DOI: 10.1016/j.dld.2008.09.008]. 被引量:1
  • 5Eisig JN, Silva FM, garbuti RC, Rodriguez TN, Mal- fertheiner P, Moraes Filho JP, Zaterka S. Efficacy of a 7-day course of furazolidone, levofloxacin, and lansoprazole after failed Helicobacter pylori eradication. BMC Gastroenterol 2009; 9:38 [PMID: 19470177 DOI: 10.1186/1471-230X-9-38]. 被引量:1
  • 6Sezikli M, Cetinkaya ZA, Sezikli H, Gtizelbulut F, Tiftikci A, Ince AT, GOkden Y, Yasar B, Atalay S, Kurdas OO. Oxidative stress in Helicobacter pylori infection: does supplementation with vitamins C and E increase the eradication rate? Helicobacter 2009; 14:280-285 [PMID: 19674132 DOI: 10.1111/ j.1523-5378.2009.00686.x]. 被引量:1
  • 7Fuccio L, Eusebi LH, Zagari RM, Bazzoli F. Heli- cobacter pylori eradication treatment reduces but does not abolish the risk of gastric cancer. Am J Gastroentero12009; 104: 3100; author reply 3101-3102 [PMID: 19956126 DOh 10.1038/ajg.2009.516]. 被引量:1
  • 8Kim BG, Lee DH, Ye BD, Lee KH, Kim BW, Kim SG, Kim SW, Kim SK, Kim JJ, Kim HY, Park JJ, Park CY, Baik GH, Lee YC, Lee JH, Lee JH, Chun HJ, Hahm KB, Hong SJ, Lee SW, Jung HC. Compari- son of 7-day and 14-day proton pump inhibitor- containing triple therapy for Helicobacter pylori eradication: neither treatment duration provides acceptable eradication rate in Korea. Helicobacter 2007; 12:31-35 [PMID: 17241298 DOI: 10.1111/ j.1523-5378.2007.00468.x]. 被引量:1
  • 9Uotani T, Sugimoto M, Nishino M, Kodaira C, Yamade M, Sahara S, Yamada T, Osawa S, Sugimo- to K, Tanaka T, Umemura K, Watanabe H, Miya- jima H, Furuta T. Ability of rabeprazole to prevent gastric mucosal damage from clopidogrel and low doses of aspirin depends on CYP2C19 genotype. Clin Gastroenterol Hepato12012; 10:879-885.e2 [PMID: 22542748]. 被引量:1
  • 10Datta S, Chattopadhyay S, Patra R, De R, Ramamur- thy T, Hembram J, Chowdhury A, Bhattacharya SK, Berg DE, Nair GB, Mukhopadhyay AK. Most Heli- cobacter pylori strains of Kolkata in India are resis- tant to metronldazole but susceptible to other drugs commonly used for eradication and ulcer therapy. Aliment Pharmacol Ther 2005; 22:51-57 [PMID: 15963080 DOI: 10.1111/j.1365-2036.2005.02533.x]. 被引量:1

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