摘要
目的:综合评价孕晚期注射乙肝免疫球蛋白阻断乙肝病毒宫内感染的效果和安全性。方法:应用Revman 4.2.10软件,对计算机检索后筛选出的5项随机对照研究采用固定模型进行分析。结果:孕晚期注射HB IG组宫内感染发生率显著低于对照组[RR=0.40,95%CI(0.30,0.54)]。结论:孕晚期注射乙肝免疫球蛋白可有效地阻断乙肝病毒宫内感染。
Objective：To evaluate the efficacy and security of hepatitis B immunoglo-bulin on blocking intrauterine infection of HBV during the pregnancy third-trimester.Methods：Fix and random effect meta-analysis was applied to analyse the data of 5 randomized controlled trials,using software Revman 4.2.10.Results：Babies born from pregnant women who received hepatitis B immunoglobulin during the pregnancy third-trimester had significant lower intraute-rine transmission rate than those not[RR=0.40,95%CI（0.30,0.54）].Conclusion：Injection of hepatitis B immunoglobulin during the pregnancy third-trimester can decrease intrauterine infection rate of HBV.
出处
《现代妇产科进展》
CSCD
北大核心
2009年第3期197-200,共4页
Progress in Obstetrics and Gynecology
关键词
乙型肝炎免疫球蛋白
肝炎病毒
乙型
宫内感染
妊娠末期
META分析
Hepatitis B immunoglobulin
Hepatitis B virus
Intrauterine transmission
Pregnancy trimester
third
Meta-analysis
