摘要
目的探讨早发型重度子痫前期期待治疗时间及其妊娠结局。方法回顾性分析1998年1月至2008年1月,西安交通大学医学院第一附属医院收治的106例早发型重度子痫前期(≤32周)病例,按入院后期待治疗时间分为3组,A组(35例)治疗时间≤48h;B组(36例)治疗时间7～10d;C组(35例)治疗时间≥14d。比较不同期待治疗时间与妊娠结局的关系,包括围生儿结局及严重并发症发生情况。结果(1)围生儿死亡情况:A组早产儿死亡6例(17.14%),B组2例(5.56%),C组2例(5.71%)。A组早产儿病死率明显高于B、C组(P<0.01)。(2)并发症发生率依次为胎盘早剥、肾功能衰竭、子痫。A、B、C3组胎盘早剥发生率分别为:8.57%、8.33%及20%,肾功能衰竭及子痫发生率分别为:5.71%、5.56%及8.57%,上述指标C组均高于A、B组(P<0.05)。结论早发型重度子痫前期严密监测下期待治疗7～10d可明显降低围生儿死亡率,改善围生儿结局,而孕产妇并发症的发生率无明显增加。
Objective To investigate the period of expectant management and pregnancy outcome in early onset severe pre - eelampsia. Methods Totally 106 pregnant women meeting the criteria of early onset severe p re - eelarnpsia were enrolled in this study from Jan 1998 to Jan 2008. According to period of expectant management , all patients were divided into three groups： period of expectant management less than 48h （group A, 35 eases） ,7 - 10days（ group B ,36 eases ） and more than 14days （group C ,35 eases ）. Analyze the relationship between period of expectant management and pregnancy outcome , including maternal complication and perinatal outcomes. Results （1）The perinatal fetal death was 6 eases ,2 eases and 2 eases in three groups , respectively. The perinatal fetal mortality was the highest in group A. （2） The commonest maternal complications in turn were placental abruption, renal function failure and eelampsia. The rate of placental abruption was 8. 57% ,8.33 % and 20% , respectively, which was higher in groupe than group, A and group B （P 〈 0. 01 ）. The rate of renal function failure was 5.71% ,5.56% and 8.57% , respectively,which was higher in group C than in group A and group B （ P 〈 0.05）. The rate of eelampsia was the same as renal function failure. Conclusion The period of expectant management for 7 - 10days may be carried out in well selected patients with early onset severe pre -eclampsia, which may decrease perinatal fetal mortality and benefit the fetus without an increased risk to the mother.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2009年第4期293-294,共2页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
早发型重度子痫前期
期待治疗
妊娠结局
early onset severe pre-eelampsia
expectant management
pregnancy outcome
