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三维适形放疗同步化疗治疗局部晚期非小细胞肺癌的疗效分析

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摘要 目的:观察三维适形放疗(3D—CRT)配合化疗(方案:泰素加卡铂方案)治疗局部晚期非小细胞肺癌(NSCLC)的疗效及并发症,评价其临床价值。方法:75例经病理或组织细胞学证实的局部晚期非小细胞肺癌(Ⅲa或Ⅲb)分为两组。单纯放疗组和联合化疗组。39例进入联合化疗组,全组患者均经化疗(泰素175mg/m^2,卡铂AUC5-6,第1、22天)加3D—CRT同步治疗。单纯放疗组36例作对照单行3D—CRT治疗。结果:总有效率(CR+PR)联合组为69.23%.单纯3D—CRT组为41.67%(P〈0.05)。中位生存期分别为20个月和13个月(P〈0.05)。联合组白细胞下降发生率为71.35%,放射性食管炎为58.97%,放射性肺炎为58.97%,但经对症治疗都能完成治疗计划。结论:三维适形放射治疗联合化疗治疗局部晚期非小细胞肺癌能完成治疗计划,有望延长生存期。
作者 史冬梅
出处 《中国当代医药》 2009年第6期27-28,共2页 China Modern Medicine
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