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356例儿童支气管哮喘5年随访观察 被引量:5

Five-year follow-up study of 356 children with asthma
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摘要 目的探讨农村地区儿童哮喘的转归和影响预后的因素。方法建立住院或门诊就医的哮喘患儿档案,对356例随访档案进行整理,分析哮喘与多因素的关系。结果哮喘停止发作2年以上239例,占67.1%;5年仍在发作的117例,占32.9%。发病诱因以下呼吸道感染最多。停止发作的相关因素中,下呼吸道感染所诱发的哮喘缓解率最高,达81.3%;肺炎支原体感染所诱发占第2位,达68.5%;有过敏性鼻炎、湿疹等特应性疾病所诱发的最低,为32.8%;长期规范化治疗与其他治疗方法在缓解率方面差异无统计学意义(P>0.05);5年后仍在发作的患儿中,个人为特应质、父母有哮喘史和嗜酸性细胞(EOS)升高是哮喘持续发作的主要相关性因素(P<0.01)。结论感染性哮喘症状持续至学龄期多数可缓解;哮喘长期发作的主要危险指标为父母有哮喘病史、个人为特应质者。
出处 《临床儿科杂志》 CAS CSCD 北大核心 2009年第3期271-273,共3页 Journal of Clinical Pediatrics
关键词 哮喘 儿童 随访 asthma children follow-up
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