摘要
目的观察胃癌患者血浆纤维蛋白原水平与肿瘤临床分期、浸润程度和淋巴结转移的关系。方法结合临床资料,回顾分析我科收治的1064例胃癌患者的血浆中纤维蛋白原含量。结果血浆纤维蛋白原和胃癌分化程度、TNM分期、浸润深度、淋巴结转移及是否有远处转移有密切关系。PN0～PN3血浆纤维蛋白原水平分别为(2.43±0.74)g/L,(3.57±1.16)g/L,(3.98±0.81)g/L,(4.52±0.74)g/L。多因素Logistic回归分析表明高纤维蛋白原血症是胃癌淋巴结转移的一个危险因素。结论术前血浆纤维蛋白原水平可以作为预测胃癌淋巴结转移的一个指标。
Objective To investigate the correlation of plasma level of fibrinogen with clinical stage, depth of invasion and lymphatic metastasis of gastric malignant tumors. Methods Preoperative plasma levels of fibrinogen were retrospectively analyzed in 1064 gastric cancer patients who were diagnosed by pathology. Results Fibrinogen showed a significant correlation with tumor differentiation, TNM stage, depth of invasion, lymphatic metastasis and distant metastasis in gastric cancer. The level of plasma fihrinogen in PN0 - PN3 was （2.43±0.74）g/L, （3.57 ± 1.16） g/L, （3.98 ±0. 81 ） g/L, （4.52±0. 74） g/L respectively. Multivariate analysis revealed that plasma fibrinogen level was a risk factor of lymphatic metastasis in gastric cancer patients. Conclusions Preoperative plasma fibrinogen level is a useful predictor of lymphatic metastasis in gastric cancer.
出处
《医学信息（手术学分册）》
2008年第12期1094-1095,1098,共3页
Medical Information Operations Sciences Fascicule
关键词
胃癌
纤维蛋白原
淋巴转移
gastric carcinoma
fibrinogen
lymphatic metastasis
