摘要
目的探讨功能性消化不良患者的焦虑抑郁情绪状况，评价抗抑郁剂治疗功能性消化不良伴焦虑抑郁情绪患者的临床疗效。方法对200例功能性消化不良患者采用焦虑自评量表、抑郁自评量表评定焦虑抑郁状况；对32例伴有焦虑抑郁情绪的顽固性功能性消化不良患者给予SSRI类抗抑郁剂治疗，观察8w。于治疗前后采用症状自评量表评定患者躯体化、抑郁、焦虑因子的变化。结果200例功能性消化不良患者中92例（46％）存在不同程度的情绪障碍；32例顽固性功能性消化不良患者抗抑郁剂治疗8w末，症状自评量表躯体化、抑郁、焦虑因子分均较治疗前有显著下降（P〈0．01）。结论功能性消化不良患者普遍存在焦虑抑郁情绪，抗抑郁治疗能显著改善患者的症状。
Objective To investigate the effect of psychological factors and curative effect of antidepressant on functional dyspepsia（FD）. Methods 200 FD patients were assessed with SCL-90, SDS and SAS. Antidepressants were used to treat 32 refractory FD patients for 8 weeks, and mental status were evaluated before and after the treatment. Results There was 46%0 FD patients combined with depressive or anxious emotion. Compared with pre-treatment, the mental and physical symptoms in refractory FD patients improved significantly post-treatment. Conclusion The FD patients with depression or anxiety are prevalence, and antidepressants can improve their somatic and psychological symptoms.
出处
《临床心身疾病杂志》
CAS
2009年第1期53-54,共2页
Journal of Clinical Psychosomatic Diseases
