摘要
旋转叶轮泵的发展使研制新型全人工心脏成为可能。本文通过模型样机研制和流体力学特性测试,探索以叶轮式血泵为结构基础的新型全人工心脏。新研制的全人工心脏样机采用两个轴流泵作为基本单位共同设置在筒形外壳中,不需压力补偿腔。外壳由钛合金制成,直径65mm,长度70 mm。在体外模拟循环台上采用持续输出和搏动输出两中方式对左心泵和右心泵的的转速,输出压力,流量,能耗和效率特性进行测试。模拟循环装置由模拟左,右心房,血泵,阻力调节器,流量计串联组成,采用30%甘油水溶液作为循环介质。通过调节阻力测定特定泵转速下压力和流量。采用ST3PR式时间继电器周期性导通电源对泵电机绕组间隙性馈电。体外模拟测试表明全人工心脏在搏动输出条件下可满足机体的血液动力学基本要求,左心泵在14700 r/min的最高转速条件下可以达到5L/min流量和100mmHg的压力输出,右心泵在约8000rpm转速和25mmHg后负荷下达到相似流量,可满足肺循环的要求.总功耗能12瓦,效率约10%。本研究结果表明叶轮泵式全人工心脏可实现搏动输出,流体力学特性可达到全人工心脏的基本要求。
Rotary blood pumps make it possible to develop newer cardiac replacement devices with entirely different configurations.Under investigation are total artificial heart by utilizing axial pump we developed before. The axial pumps were enclosed in a single cylindric crust which had a good anatomic fit. The rotational speed and output of left and fight pump was designed to be regulated separately to accommodate the pulmonary and systemic circulation respectively, and compliance chamber was not necessary. A prototype, 65mm in diameter and 70mm in length, was made and tested in a mock circulation system. The 30% glycerol solution was used as a working fluid. Pump flow rate were measured by manually regulating the resistance to change the head pressure for a given rotational speed. In the continous mode, The left pump worked at a rotational speed of 13000rpm with a flow rate 5L/min against 100mmHg afterload while the right pump deliver the same flow against 25mmHg at 8000rpm. A relay of mode ST3 PR was employed to control the power supply to the electric pump in a periodic pattern, resulting in a fluctuate pump output. However, the maxmim rotary speed for a pulsation outflow reaches 14700rpm for same flow rate. The observed total efficiency of the artificial heart was 10% with power consumption of 12 watts at that time. This pilot studies clarified the further feasibility of this system and indicate that the pulsatily control of the total artificial heart is feasible.
出处
《中国医疗器械信息》
2009年第3期26-28,共3页
China Medical Device Information
关键词
心脏辅助装置
人工心脏
轴流泵
心功能衰竭
Heart Assist Device, Total Artificial Heart, Axial Flow Pump, Cardiac Failure
