摘要
目的:观察中药熏蒸疗法治疗强直性脊柱炎(AS)临床疗效。方法:以随机开放性研究的原则,将40例AS患者分为熏蒸组(20例)和非熏组(20例),非熏组给予每日美洛昔康7.5mg、每周甲氨喋呤10mg和每日香丹针20ml静脉滴注;熏蒸组在非熏组治疗基础上加用熏蒸2号方熏蒸治疗,每次20min,每天1次,连续20d。结果:①熏蒸组与非熏组总有效率比较差异无统计学意义(P>0.05),但熏蒸组的显效率明显优于非熏组(P<0.05。②两组治疗前后在疼痛指数、压痛指数、关节功能指数、活动障碍指数和晨僵时间均有明显改善(P<0.05),而且,熏蒸组明显优于非熏组(P<0.01)。③两组治疗前后急性炎症指标(ESR、CRP)均有明显改善(P<0.01),且熏蒸组优于非熏组(P<0.05)。④熏蒸组无明显不良反应。结论:中药熏蒸疗法具有改善AS的临床症状、体征及急性炎症指标的作用,且安全性良好。
Objective：To observe the Chinese herb fumigation and steaming therapy for ankylosing spondylitis （AS）. Methods：Forty patients with AS were divided into 2 groups randomly： Group A （n= 20） were treated with conventional therapy （Meloxicam 7.5mg/d ＋ MTX 10mg/w ＋ Xiangdan Injection 20ml/d）, while Group B （n= 20） were treated with conventional therapy plus Chinese herb fumigation and steaming 20 minutes a day for 20 days. Results： There was no significant difference in total effective rate between the 2 groups （P〉0.05）, but the excellent effective rate in Group B was remarkably higher than that in Group A （P〈0.05）. Moreover, the scores of pain, tenderness, general function, restricted activities of vertebral column and time of morning stiffness as well as acute inflammatory indexes （ESR, CRP） were obviously improved as compared with before the treatment （P〈0.05）, with better results in Group B than in Group A （P〈0.05）. No obvious adverse reaction was found in Group B. Conclusion：The Chinese herb fumigation and steaming therapy can improve the symptoms, signs and acute inflammatory indexes of AS with good security.
出处
《中国中医骨伤科杂志》
CAS
2009年第3期27-28,31,共3页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
基金
广东省自然科学基金资助课题:中药熏蒸治疗胶原诱导型关节炎大鼠的抗炎机理研究(代码:5001002
顺序号:06019700)
关键词
中药熏蒸疗法
强直性脊柱炎
熏蒸2号方
The Chinese herb fumigation and steaming therapy
Ankylosing spondylitis
Xunzhengfang 2
