摘要
对67例急性心肌梗塞（AMI）合并Ⅱ型糖尿病病人（DM－AMI组），和按其一般情况及梗塞部位配对的无DM的AMI病人67例（NDM－AMI组）进行比较研究。结果显示：两组的肌酸磷酸激酶（CPK）峰值、心电图QRS记分均无显著性差异，但DM－AMI组住院期间的死亡率及严重心脏事件的发生率均高于NDM－AMI组，梗塞后4周和6个月时的左室舒张末容量（LVEDV）及收缩末容量（LVESV）显著高于NDM－AMI组，而左室射血分数（LVEF）则明显低于NDM－AMI组，提示AMI病人合并DM者左心功能及临床预后均较不合并DM者差，可能与合并的DM性心肌病有关。
Sixty- seven diabetic (DM-AMI group) and 67 nondiabetic patients (NDM- AMI group) With acute myocardial infarction (AMI) matched for age, sex,myocardial infarct site were studied. The incidence of severe cardiac events was significantly higher in DM- AMI group than in NDM AMI group. The in-hospital mortality of DM- AMI group and NDM-AMI group was 6. 0% and 1. 5 %,respectively(P >0.05). Left ventricular end-diastolic volume(EDV) by 2-dimension echocardiography in DM-AMI group and in NDM-AMI group at 4 weeks after infarction was 85. 4± 13. 2 and 75. 4 ± 11. lml (P <0. 001 ),left ventricular end-systolic volume (ESV) 49. 1 ± 1 1. 1 and 40. 3 ± 11. 3ml (P〈 O. 001 ), left ventricular ejection fraction (LVEF) 42. 8 ± 5. 6 % and 46. 6 ± 7. 1 % (P〈O. 01 ), respectively. The EDV in DM-AMI group and in NDM- AMI group at 6 months after infarction was 98. 7± 26. 5 and 83. 9± 10. 8(P 〈O. 001 ),ESV 55. 9± 30. 7 and 38. 4±14. 3ml(P <0. 001 ),LVEF 43. 1±1 14. 3% and 54. 4± 10. 1 % (P 〈O. 001 ,respectively. Compared with NDM-AMI group,LVEF increased more significantly from 4 weeks to 6 months in DM-AMI group(P< O. 01 vs P >0. 05 ). The incidence of left ventricular aneurysm was higher in DM-MI group than in NDM- AMI group (25. 4 % vs 12. 7%, P >0. 05). It is concluded that diabetic patient with AMI has a lower left ventricular function and poorer short term prognosis and diabetic cardiomyopathy is probably responsible for it.
出处
《中国糖尿病杂志》
CAS
CSCD
1998年第2期74-77,共4页
Chinese Journal of Diabetes
关键词
急性
心肌梗塞
左心功能
糖尿病
Acute myocardial infarction Left ventricular function
