摘要
目的回顾性调查昆明市近10年炎症性肠病（IBD）患者的发病状况。方法调查1998年1月-2007年3月七家综合性医院430例住院IBD患者，其中溃疡性结肠炎（UC）379例，克罗恩病（CD）51例。接受结肠镜、组织病理学和钡剂灌肠检查者在UC和CD患者中分别为98．2％和56．2％、2．6％和72．5％、78．4％和31．4％。对IBD患者的年龄、性别、职业、临床表现、内镜和组织病理学检查结果进行分析。结果UC患者平均年龄为（46．9±15．8）岁，以30～39岁和50～59岁年龄段患者最多，呈双峰状分布；CD患者平均年龄为（41．6±17．2）岁，以20～29岁年龄段患者最多。UC和CD患者均以男性为主，UC患者中脑力劳动者多见。UC患者以腹泻（302，79．7％）、腹痛（285，75．2％）、血便（290，76．5％）为主。CD患者常见腹痛（44，86．3%）、腹泻（28，54．9％）、体重减轻（28，54．9%）。UC患者内镜检查、病理检查、钡剂灌肠诊断符合率分别为88．4％（329／372）、24．4％（52／213）、4／10，CD患者分别为86．5％（32／37）、27．5%（11／40）、75%（12／16）。UC患者100%为活动期，其中轻、中、重度分别为38．3％、42．2％和19．5％。CD患者活动期占92．2％，缓解期占7．8％，其中轻、中、重度者分别为15．7％、43．1％41.2％。结论了解10年来昆明市的IBD发病情况及临床特征将有助于临床诊断和治疗。
Objective To retrospectively investigate the characteristics of patients with inflammatory bowel disease （IBD）in last 10 years in Kunming city. Methods Four hundred and thirty consecutive patients with IBD, who had hospitalized in 7 hospitals between January 1998 to March 2007, were investigated. Among them, 379 patinets had ulcerative colitis （UC） and 51 had Crohn＇s disease （CD）. The patients who received coloscopy, histopathological and bariam enema examination accunted for 98.2%, 56.2% and 2.6% in UC group,respectively, arid 72.5%,78.4% and 31.4% in CD group,respectively. The gender, age, occupation and the clinical manifestation of the patients, and the results of the eolonoscopy and pathological examination were analyzed. Results Most of the UC patients were aged 30 to 39 years and 50 to 59 years with average age of （46.9±15.8） years, whereas CD patients were aged 20 to 29 years with average age of （41. 6 ± 17.2）years. The male and urban patients were predominat in both UC and CD groups. Mental workers were common in UC group. The symptoms of diarrhea （302,79.7%）, abdominal pain （285,75.2%） and bloody stools （290,76.5%） were major events in UC patients, and those of abdominal pain （44,86.3%）, diarrhea （28,54.9%） and weight loss （28,54.9%） were major events in CD patients. The coincidence ratio among colonoscopy, histopathology and bariam enema examinations was 88.4 % （329/372 ）, 24.4 % （ 52/213 ） and 4/10 in UC patients, respectively, and 86.5%（32/37）, 27.5%（11/40） and 75%（12/16） in CD patients,respectively. All of the UC patients were in active stage of disease,including 38.3 % in mild, 42.2% in moderate and 19.5% in severe. In CD group, 7.8% was in relief stage and 92.2% in active stage,including 15. 7% in mild, 43. 1% in morderate and 41. 2% in severe. Conclusion The understanding of prevalence and clinical characteristics of IBD in last 10 years in Kunming city will be helpful in diagnosis and treatment of the disease.
出处
《中华消化杂志》
CAS
CSCD
北大核心
2009年第2期90-92,共3页
Chinese Journal of Digestion
关键词
溃疡性结肠炎
克罗恩病
诊断
Inflammatory bowel diseases
Crohn＇s disease
Diagnosis
