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左旋肉碱对终末期肾病患者微炎症状态的影响 被引量:7

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摘要 目的通过观察静脉注射左旋肉碱(L-CN)对终末期肾病(ESRD)患者相关营养和炎症指标的影响,探讨L-CN对ESRD患者微炎症的治疗作用。方法入选透析患者34例为透析组和非透析患者40例为非透析组,透析组和非透极组又各自分为治疗组和对照组两个亚组,治疗组给予L-CN1g/20ml静脉注射,对照组则给予等体积生理盐水20ml静脉注射,每周3次,随访3个月,分别检测治疗前、治疗3个月后患者的C反应蛋白(CRP)、血常规、血生化指标、透析充分性(Kt/V)。结果治疗后,透析和非透析组中,与治疗前比较,治疗组治疗后各项指标明显改善,差异显著,对照组治疗后无明显变化。结论L-CN可明显改善患者的营养状态,纠正贫血,同时降低血CRP浓度,改善患者炎症状态。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2009年第4期467-469,共3页 Chinese Journal of Gerontology
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参考文献16

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