摘要
目的比较诺和锐30与诺和灵30R控制2型糖尿病餐后血糖的差异。方法采用随机临床对照试验的方法,将40例2型糖尿病患者随机分为诺和锐30组和诺和灵30R组,分别皮下注射诺和锐30胰岛素和诺和灵30R胰岛素,监测两组患者空腹及餐后血糖控制情况,并进行分析比较。结果两组患者治疗前空腹血糖、餐后血糖值无明显差异,治疗后两组患者空腹血糖值无差异,餐后血糖值差异有统计学意义(P<0.05)。诺和锐30胰岛素组低血糖发生率少。结论诺和锐30控制餐后血糖的作用优于诺和灵30R,低血糖发生率少。
Objective To compare the difference of efficacy between biphsic insulin aspart 30 （30% fast-acting and 70% protamineerystallised insulin aspart , BIAsp30） and biphsic human insulin 30 （30% regular insulin and 70% NPH insulin , BHI 30） in the patients with type 2 diabetes. Methods Forty cases of inadequate glucose control by oral antidiabetic drug were randomly divided into two groups using twice-daily insulin comparison of BIAsp30 and BHI30. Efficacy was assessed after 120 days. Results Significant improvements was observed in postprandial glucose control by using BIAsp30 （P〈0.05） and with lower incidence of hypoglucose .there was no difference in fasting glucose control between two kinds of insulin.Conclusion The rapid-acting insulin analog is superior to regular insulin in controlling postprandial glucose, with lower incidence of hypoglucose.
出处
《当代医学》
2009年第3期11-12,共2页
Contemporary Medicine
