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开搏通、可乐宁对高血压大鼠视网膜病变疗效的超微结构观察 被引量:1

EFFECT OF CAPTOPRIL AND CLONIDINE ON ULTRASTRUCTURE OF RETINA IN HYPERTENSIVE RATS
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摘要 应用光、电镜观察高血压大鼠经开搏通和可乐宁终身治疗后.其视网膜超微结构病变改善情况.结果表明:高血压大鼠视网膜超微结构的改变主要在视细胞外节,内节,神经节细胞的胞体和轴突.经开搏通终身治疗后视网膜超微结构病变得以改善,而经可乐宁治疗则无明显改变, 为高血压患者的早期预防和治疗提供重要参考. The retinal ultrastructure of the spontaneously hypertensive rats (SHR) admini.stered with captopril and clonidine life time were observed by means of light and transmission electron microscopy in this paper. The results showed that the pathological changes of the retina appeared mainly in the outer and inner segments of the photoreceptors. ganglionic cells and their axons. The pathological changes of the retinal ultrastructure of SHR administered with captopril life time were improved, which those of the SHR administered with clonidine life time were not distinctly improved.
出处 《解剖学杂志》 CAS CSCD 北大核心 1998年第2期158-161,共4页 Chinese Journal of Anatomy
关键词 高血压 视网膜病变 药物疗法 开搏通 可乐宁 spontaneous hypertensire rat retina captopril clonidine
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