摘要
目的探讨外周动脉留置针所致血管动脉瘤和血栓的病理改变及其与留置针封管次数和封管液浓度的相关性,以确定合适的封管次数和封管液浓度,减少动脉留置针造成血管损伤的因素。方法将种系相同,体重相近的大耳新西兰健康白兔随机分成三组,每组10只,取兔双耳的中央动脉作为实验血管,置动脉留置针。分别采用不同的封管液浓度和封管次数,各组均保留至96 h,以穿刺点为起点向上沿留置动脉方向取2 cm×1 cm含穿刺动脉血管和耳廓组织的标本做病理切片,观察动脉血管的病理变化。结果三组动脉瘤发生率分别为20%、65%和55%,第一和第二组动脉瘤发生率经χ2检验,χ2=6.99,P<0.01,差异有极显著意义;第二和第三组动脉瘤发生率经χ2检验,χ2=0.921,P>0.05,差异无显著性意义。三组血栓发生率分别为30%、40%和35%,经χ2检验差异无显著性意义。结论封管次数与动脉瘤产生呈正相关;改变封管液浓度和封管次数,不能有效降低血栓的发生率。
Objective To study the pathological changes of aneurysm and thrombosis caused by peripheral artery catheter, and it＇s relationship with closure time and concentration of closure liquid for reducing the factors lead to the damage caused by artery catheter. Method Similar weight and species health big ear New Zealand rabbits was selected and divided into three groups. Each group has 10 rabbits. The central artery of double was selected as experimental vascular and indwelling artery catheter. Different time of closure and concentration of closure liquid was adapted respectively. Indwelling artery catheter in each group was reserved for 96 h. Spices of was taken from 2 cm× 1 cm punctured vascular and auricle to observe the pathological changes of artery vascular. Result The occurrence rate of aneurysm in three groups was 20%, 65% and 55%. The occurrence rate of aneurysm thrombosis in group and group 2 was significant difference （P〈0.01）. There was no significant difference in occurrence rate of thrombosis between group 2 and group 3 （P〉0.05）. The occurrence rate of thrombosis in three group was 30%, 40% and 35 % respectively. There was no significant difference. Conclusion There is positive correlation between closure time and occurrence of aneurysm. Change of colure time and concentration of closure liquid will not reduce effectively the occurrence rate of thrombosis.
出处
《护士进修杂志》
北大核心
2008年第19期1740-1742,共3页
Journal of Nurses Training
基金
2006年河北医科大学第二医院科研项目
课题号:Zho200605
关键词
动脉留置针
血栓
动脉瘤
Artery catheter Thrombosis Aneurysm
