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热休克蛋白47与纤维化相关疾病研究进展 被引量:4

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摘要 肝纤维化、皮肤病理性瘢痕等纤维化相关疾病以Fb增殖和大量ECM聚集(主要是胶原蛋白过度沉积)为主要特征。热休克蛋白47(HSP47)是一种定位在细胞内质网中的小分子HSP,与其他HSP不同,它特异作用于胶原蛋白家族,参与胶原蛋白前体的合成、分泌和成熟过程,为胶原合成所必需。
出处 《中华烧伤杂志》 CAS CSCD 北大核心 2009年第1期75-78,共4页 Chinese Journal of Burns
基金 国家自然科学基金(71003202)
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参考文献23

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二级参考文献18

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