摘要
目的对流行性奈瑟氏脑脊髓膜炎(简称流脑)疑似病例检测结果进行分析,为流脑监测提供依据。方法对155例流脑疑似病例进行全血培养、脑脊液培养、流脑特异性抗原、流脑DNA、急性期和恢复期IgG抗体检测。比较检测结果的阳性率。结果155例流脑疑似病例中实验室确诊79例,阳性率54.1%;其中流脑C群为77例占97.5%。密切接触者带菌129例,阳性率为8.1%;其中C群为103例占79.8%。样本和样本组合阳性率以双份血清阳性率最高,脑脊液阳性率次之,血培养阳性率最低。结论C群流脑仍然占绝对优势,密切接触者菌群与流行病例一致。考虑到快速诊断的要求,样本采集中,应以脑脊液和双份血清为主。
Objective To analyze Laboratory results of ECM suspect cases and provide the basis for epidemic cerebrospinal meningitis Surveillance. Methods Blood and cerebrospinal fluid Samples in acute phase and convalescence phase of 155 ECM suspect cases were cultivated or detected for Neisseria meningitis and its Antigen, DNA and IgG antibody. Detection results were compared. Result 79 examples were made a definite diagnosis in the laboratory among the 155 suspect eases with positive rate of 54.1%. Of them, C serogroup accounted for 97.5%. Positive rate of 129 close contacts was 8. 1%. Of them, C serogroup accounted for 79.8% 103/129. Positive rate of blood samples ranked the first. Positive rate of cerebrospinal fluid Samples ranked the second. Positive rate of blood cultivation was the lowest. Conclusion C serogroup was still the predominant serogToup of ECM. Detection results of close contacts were consistent with that of the suspect cases. In order to meet rapid diagnosis, cerebrospinal fluid and double blood examples are needed to collect.
出处
《安徽预防医学杂志》
2009年第1期37-38,共2页
Anhui Journal of Preventive Medicine
