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异体血细胞移植在骨科治疗中的应用现状

Application status of allogenic blood transfusion in orthopedics treatment
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摘要 异体血细胞移植在骨科大手术中的应用越来越广泛,如何正确的使用异体血细胞移植这一方式是每个骨科医生必然要面临的临床问题。异体血细胞移植本身所带来的并发症不是人为所能控制的,如何正确的使用血液以及是否会有新的替代品替代异体血细胞移植,也是现今医学的一个方向。中药的一些成分对于人体造血系统是否有很大的影响,或者说在某些程度上可以补充血液的不足也是一个新的问题。 Tissue engineering may allow obtaining patient's own cells, seeding them on biodegradable scaffolds, thus achieving formation of a particular tissue or organs, such as bone, cartilage, muscle, or heart. These tissues or organs can be used to repair tissue or organs defects caused by disease or trauma. Many animal studies have demonstrated the efficacy of using bone marrow mesenchymal stem cells in treatment of diseases such as nervous system diseases, liver disease, respiratory diseases and kidney disease. The main ways of the stem cells therapy are local implantation and systemic transplantation of bone marrow mesenchymal stem cells, and the effect of such treatments is notable. The use of gene-modified stein cells in gene therapy is an fantastic option due to theoretical advantage of stem cells compared to somatic cells with respect to higher proliferative capacity. Bone marrow mesenchymal stem cells can deliver genes and proteins into organs or tissues with specific need for gene therapy.
出处 《中国组织工程研究与临床康复》 CAS CSCD 北大核心 2008年第B12期10531-10534,共4页 Journal of Clinical Rehabilitative Tissue Engineering Research
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参考文献31

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