摘要
在对甲苯磷酸存在下,采用1,1-二[4-(N,N-二取代氨基)苯基]乙烯(3)和四氯苯酐在乙酸酐溶液中的缩合反应合成了3,3-二{2,2-二[4-(N,N-二取代氨基)苯基]乙烯基}-4,5,6,7-四氯-2-苯并[c]呋喃酮(4),产率89～93％。3由4,4＇-二(N,N-二取代氨基)二苯甲酮(1)与甲基碘化镁进行Grignard反应的产物经水解再脱水制得,产率85％～88.5％(以1为基准)。
3,3- Bis [ 1,1 - bis (4 - disubstituted aminophenyl) ethylen - 2 - yl ] - 4,5,6,7- te-trachlorophthalides(4) were synthesized by the condensation of tetrachlorophthalic anhydride with 1,1- bis(4 - disubstituted aminophenyl)ethylenes(3) in acetic anhydride in the presence of p - toluene-sulfonic acid, yields 89% - 93 % . Compound 3 were prepared by the dehydration of 1,1 - bis(4 - disubstituted aminophenyl)ethanols(2) which were synthesized by Grignard reaction of 4,4' - bis(N,N- disubstituted amino) benzophenones (1) with methyl magnesium iodide, yields 85 % -88.5 % (based on 1).
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
1998年第2期175-179,共5页
Chinese Journal of Organic Chemistry
基金
黑龙江省自然科学基金
关键词
二烯基
四氯
苯并
呋喃酮
合成
热敏染料
3
3-bis[1
1 -bis(4- disubstituted aminophenyl)ethylen-2- yl] -4
5
6
7- te-trachlorophthalides
tetrachlorophthalic anhydride
1
1- bis(4 - disubstituted aminophenyl)ethylenes
4
4' -bis(N
N- disubstituted amino)bezophenones
Grignard reaction
