摘要
目的对比正常人群，评价血脂异常人群颈动脉内中膜厚度及血清基质金属蛋白酶-9水平，并分析其相关性。方法选择血脂异常患者77例对比正常健康人群82例，以超声测定入选人群颈动脉内中膜厚度，双抗体夹心酶联免疫吸附试验法检测入选者血清基质金属蛋白酶-9水平，并分析两者相关性。结果血脂异常患者颈动脉内中膜厚度（1．17±0．19）mm及血清基质金属蛋白酶-9水平（803．37±91．28）ng／ml经统计明显高于对照组颈动脉内中膜厚度（0．61±0．12）mm及血清基质金属蛋白酶-9水平（352．81±19．26）ng/ml，P〈0．05。结论血脂异常人群颈动脉内中膜厚度及血清基质金属蛋白酶-9水平增高，颈动脉内中膜厚度及血清基质金属蛋白酶-9可能是反应血脂异常人群早期动脉粥样硬化的指标，血脂异常人群颈动脉内中膜厚度与血清基质金属蛋白酶-9有关。
Objective To compare the normal population,the evaluation dyslipidemia population in the carotid artery in the film thickness and serum MMP-9 level and analysis of their relevance. Methods 77 cases of patients with abnormal blood lipid contrast normal healthy people in 82 cases, to selected groups of ultrasound within the carotid artery in the film thickness, double-antibody sandwich ELISA Detection selected serum MMP- 9 level and Analysis Taken relevant. Results The lipid disorders in patients with carotid artery in the film thickness（ 1.17 ± 0. 19 ）mm and serum matrix metalloproteinase-9 （ 803.37 ± 91.28 ） ng/ml, as statistics clearly higher than in the carotid artery in the film thickness（ 0. 61 ± 0. 12）mm and serum matrix metaUoproteinase-9 （352. 81 ± 19. 26 ）ng/ml, P 〈 0. 05. Conclusion dyslipidemia population in the carotid artery in the film thickness and serum MMP-9 levels increased in the carotid artery in the film thickness and serum MMP-9 may be abnormal blood lipid response to the crowd of early atherosclerosis indicators, dyslipidemia The crowd in the carotid artery in the film thickness and serum MMP-9.
出处
《中国临床实用医学》
2009年第1期58-59,共2页
China Clinical Practical Medicine
