摘要
目的：探讨地塞米松联合氟哌利多预防腹腔镜胆囊切除（LC）术后恶心呕吐的效果。方法：180例ASAⅠ-Ⅱ级LC术患者，随机分成3组，各60例，A组术前静脉注射生理盐水10 ml，B组、C组术前分别静脉注射地塞米松10 mg、地塞米松10mg和氟哌利多20μg/kg，观察术后48 h患者的恶心、呕吐情况。结果：A组恶心、呕吐的发生率为68.3%，B组、C组恶心呕吐的发生率分别为26.7%和8.3%，各组间比较差异有统计学意义（P〈0.005）。结论：地塞米松复合小剂量氟哌利多能减少术后恶心、呕吐。
Objective：To investigate the effect of dexamthasone and droperidol in prevention of postoperative nausea and vomiting （PONV） after laparoscopic cholecystectomy （ LC ）. Methods. One hundred and eighty ASA physical status Ⅰ or Ⅱ patients were randomized into three groups. Group A（ n = 60） ：Normal saline 10 ml was administered intra venous before surgery. Group B（ n = 60） ： dexamethasone 10 mg and Group C （test group, n = 60） ： dexamethasone 10 mg and droperidol 20 ug/kg were administered intra venous before surgery. The occurrence of PONV was recorded and assessed during 48 h after the surgery. Results： The incidence of PONV in group A was 68.3% ,group B and group C were 26.7% and 8.3% respectively. There were significant difference between group A and Group B, group A and group C, and Group B and group C （ P 〈 0. 005 ）. Conclusions ： Dexamethasone and the low-dose droperidol is better than dexamethasone alone and placebo in prevention of PONV after LC.
出处
《蚌埠医学院学报》
CAS
2009年第1期34-36,共3页
Journal of Bengbu Medical College
