摘要
第一章 分离方法介绍
1.1高速逆流色谱
高速逆流色谱(HSCCC)是由美国国家医学院YioehiroIto博士于1982年首先开始的。当仪器工作时互不相容的两相溶剂在绕成线圈的聚四氟乙烯管内具有单向性流体动力平衡性质。在聚四氟乙烯管内做高速行星运转时,如用其中一相溶剂做固定相,
Fatty acid synthase(FAS) is the most important enzyme in synthesis fatty in cell. FAS catalyse Ac-CoA and Mal-CoA into long chain fatty acid. To inhibit the activity of FAS, it can block and reduce the access of synthesis fatty acid and in body. At the same time, it also can increase the concentration of Mal-CoA which cause the decrease of appetite. Academe has point out that FAS is both target of treatment of cancer and obesity. But the FAS inhibitor has been discovered is very lack. Cerulenin is toxic. C75 needs very high concentration of periphery dose. EGCG has poor inhibit ability.
出处
《生命科学仪器》
2008年第12期6-9,共4页
Life Science Instruments