DREAM信号通路调控疼痛敏感化的研究进展
被引量：1
摘要
近年来通过对下游调控元件拮抗剂调节子（downstream regulatory element antagonistic modulator，DREAM）基因剔除小鼠的研究发现，在急性疼痛或慢性病理性疼痛等动物模型中，DREAM对疼痛行为的敏感化具有调控作用。存在于脊髓神经细胞中的DREAM是一种新型的Ca^2＋结合蛋白，是调控前强啡肽基因表达的转录抑制物。
出处
《实用医学杂志》
CAS
北大核心
2009年第1期151-153,共3页
The Journal of Practical Medicine
基金
广东省科技计划资助项目(编号:2008-83025)
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