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再生障碍性贫血发病机制认识的发展与启示 被引量:5

Some Enlightenment about the Development Process of Understanding the Pathogenesis of Aplastic Anemia
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摘要 再生障碍性贫血的发病机制已经突破了"种子"、"土壤"、"虫子"学说,并沿着"免疫异常"理论进入"自身免疫病"理论。同时这是一个科学思维付诸实践不断探索的过程。大量证据表明再生障碍性贫血是一种自身免疫病,它应该符合自身免疫病的共性,这一认识开阔了人们的视野,使人们能在更高的层面上考察原来的事物。 The understanding of pathogenesis of aplastie anemia has broken through the "seed, soil and insect" theory and along abnormal immune into auto immune disease. This process is accompanied by putting the scientific thinking into practice. There is growing evidence that aplastic anemia is an autoimmune disease, it certainly applies to the commonality of autoimmune disease, furthermore this new perspective will allow people to broaden their horizon and to recognize the original things at a higher level.
出处 《医学与哲学(B)》 2009年第1期62-63,74,共3页 Medicine & Philosophy(B)
基金 吉林省科技发展计划项目白求恩医学科研基金支助 项目编号:200705107
关键词 再生障碍性贫血 自身免疫病 类比 aplastie anemia, autoimmune disease, analogy
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  • 1Bernhard H,Mare J,Nobert S,et al.Degeneracy in T-cell antigen recognition-implications for the pathogenesis of autoimmune diseases[J].J Neuroimmunol,2000,107(2):148-153. 被引量:1
  • 2Scott M.Lieberman,Anne M.et al.Identification of the β cell antigen targeted by a prevalent population of pathogenic CD8^+ T cells in autoimmune diabetes[J].PNAS,2003,100(14):8384-8388. 被引量:1
  • 3Theofilopoulos AN,Dummer W,and Kono DH.T cell homeostasis and systemic autoimmunity[J].JCI,2001,108(3);335-340. 被引量:1
  • 4Maciejewski JP,Risitano AM,Kook H,et al.Immune pathophysiology of aplastic anemia[J].Int J Hematol,2002,76(Suppl 1):207-214. 被引量:1

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