摘要
目的探讨不同复方外敷液及外敷时间对预防化疗性静脉炎的作用效果。方法将2007年1月～2008年9月在本科室首次行化疗的600例肿瘤患者随机分为A、B、C3组,每组200例。3组均采用50%葡萄糖40mL+硫酸镁20mL+维生素B125000μg外敷液外敷;另外3组分别加入氢化可的松70mg、50mg、30mg;每组又分2个亚组各100例,每天分别于化疗前1h和化疗开始前外敷浸有外敷液的纱块。结果A、B、C3组静脉炎发生情况比较,差异有统计学意义,其中A、B组静脉炎的发生率明显低于C组。不同时间外敷患者静脉炎的发生率比较,差异具有统计学意义(χ2=2.8412,P=0.005),化疗前1h贴敷外敷液,患者静脉炎的发生率低于化疗开始时外敷患者静脉炎的发生率。结论采用B组复方外敷液及化疗前1h外敷,可有效预防化疗性静脉炎的发生。
Objective To explore the influence of different kinds of mixed liquid for external application and external application time on chemotherapeutic phlebitis. Methods A total of 600 patients who received chemotherapy for the first time from January 2007 to September 2008 were randomly divided into three groups （Group A, Group B and Group C）, with 200 in each group. A mixed liquid of 40 mL 50% glucose, 20 mL magnesium sulfate and 5 000 ixg Vitamin B12 was used for external application in all three groups. 70 mg, 50 mg and 30 mg of hydrocortisone were added to the liquid respectively for the three groups. In each group, 200 patients were divided into two sub-groups, with 100 in each sub-group. A lump of gauze soaked with mixed liquid was compressed on each sub-group of patients one hour before and right before chemotherapy, respectively. Results The incidence of phlebitis was significantly lower in Group A and Group B than that in Group C. The incidence of phlebitis was significantly lower in sub-groups where the liquid was applied one hour before chemotherapy than that in sub-groups where the liquid was applied right before chemotherapy. Conclusion Application of mixed liquid in Group B one hour before chemotherapy can effectively prevent phlebitis.
出处
《现代临床护理》
2009年第1期7-9,共3页
Modern Clinical Nursing
基金
黑龙江省卫生厅资助项目
项目编号2006-34。
关键词
氢化可的松
外敷液
化疗
静脉炎
hydrocortisone
mixed liquid for external application
chemotherapy
phlebitis
