摘要
58例Ⅱ-Ⅳ期口腔颌面部鳞癌患者，用卡铂（400mg／m2，第1天）、平阳霉素（6mg／m2，1～15天）、长春新碱（1．4mg／m2，1，9天）联合化疗总有效率为81．1％，其中51例化疗后施行手术治疗，其3、5年生存率分别为70．6％、67．6％。术前化疗有效者对提高生存率有重要意义，化疗后及时手术治疗是进一步提高疗效的主要途径。
58 cases of oral maxillofacial squamous cell carcinoma in stageⅢ、Ⅳ were treated with combined chemotherapy (carboplatin 400mg/m2 at lst day,PYM 6mg/m2 from 1 st to 15th day,and VCR 1.4mg/m2 at lst and gth day). The overall response rate was 81. 1 %,51 patients of these were subsequently operated and survival rate at 3, 5 years was 70. 6%, 67. 6% respectively, The results showed that preoperative reductive chemotherapy is helpful to the advanced squamous cell carcinoma in oral cavity,and surgical intervention following reductive chemotherapy is an approach to improving survival.
出处
《口腔医学纵横》
CSCD
1998年第1期32-34,共3页
Journal of Comprehensive Stomatology
关键词
鳞状细胞癌
药物疗法
口腔肿瘤
手术前
squamous cell carcinoma preoperative reductive chemotherapy carboplatin pingyangmycin vincristine
