摘要
目的观察血塞通注射液联合甲氯芬酯治疗脑梗死的临床疗效。方法选择发病72h内的脑梗死患者92例,随机分成治疗组(47例)和对照组(45例)。治疗组给予血塞通注射液500mg加入生理盐水250mL中静脉输注,每日1次,同时给予注射用盐酸甲氯芬酯400mg加入生理盐水200mL静脉输注,每日1次,连用14d。对照组仅用同剂量、同疗程的血塞通注射液。依据美国国立卫生院卒中量表(NIHSS)评分及日常生活能力(BI)评分评定神经功能缺损程度,并监测凝血功能、血脂、血糖、肝肾功能、血尿常规及心电图。结果治疗组与对照组相比,NIHSS评分在治疗后1周、2周有统计学意义(P<0.05或P<0.01);BI分值在治疗后1周、2周时有统计学意义(P<0.05),治疗后3周时差异更显著(P<0.01)。两组均未见明显不良反应。结论血塞通注射液联合甲氯芬酯治疗脑梗死患者临床疗效较好,安全性好。
Objective To investigate the effect of Xuesaitong injection with meclofenoxate hydroehloride on cerebral infarction （CI）. Methods Ninety- two patients （pts） with CI within 72 hours of onset were enrolled. They were randomly divided into treatment group （n= 47） treated with Xuesaitong injection and mectofenoxate hydrochloride for 14 days and control group （n=45） treated with Xuesaitong injection for 14 days. Therapeutic effect was evaluated by the National Institutes of Health stroke scale （NIHSS） and the Batbal index （BI）. Hemagglutination function, lipid, blood sugar, the liver and renal function, blood andurinary routine tests and electrocardiogram were detected. Results Compared with the control group,there was significant difference in NIHSS in treatment group after lweek to 3 weeks （P〈0.05 or P〈0.01）. There was no side effect in both groups. Conclusion Xuesaitong injection with meelofenoxate bydrochloride was effective and safe for CI.
出处
《中西医结合心脑血管病杂志》
2009年第1期31-32,共2页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词
脑梗死
血塞通注射液
甲氯芬酯
cerebral infarction
Xuesaitong injection
meclofenoxate hydrochloride
