摘要
目的:探讨无创双水平正压通气(BiPAP)治疗重叠综合征(OS)对近期肺动脉压力(PAP)及膈肌疲劳的改善情况。方法:26例OS患者均在常规治疗基础上进行无创双水平正压通气治疗24 h,检测治疗前、后静息状态下肺阻抗血流图,同步电阻抗呼吸仪描记胸、腹部呼吸运动曲线。结果:BiPAP治疗后患者平均PAP较治疗前明显改善(P<0.01),PAP大于20 mmHg病人4例,较治疗前(20例)显著减少(P<0.01);OS患者膈肌疲劳发生率高达73.8%,而治疗后检出率降至15.4%。结论:无创双水平正压通气治疗OS能显著降低患者近期肺动脉压,改善膈肌疲劳。
Objective To explore the effect of noninvasive Bi-level positive airway pressure ventilation（BiPAP） on diaphragmarie muscle fatigue and short-term pulmonary hypertension in overlap syndrome （OS）. Methods Twenty-six patients with OS received BiPAP for 24 hours in addition to conventional therapy ,the impedance Rheopneumogram （IPR） was recorded at rest before and after treatment, meanwhile,the chest and abdomen motion trace was also recorded by Impedance Respirograph （IRG）. Results The mean pulmonary artery pressure （PAP） level after treatment （ 19.6 ±4.8 mmHg） ,was significant lower than that before treament （28.2 ± 7.2 mmHg） （P 〈 0.01 ）. There were only 4 cases of that PAP was over 20mmHg after treatment ,which was significantly decreased than that before treatment （ P 〈 0.01 ）. The Incidence rate of diaphragmatic muscle fatigue in OS patients was 73.8%, while after treatment the ratio of diaphragmatic muscle fatigue was decreased to 15.4%. Conclusions BiPAP can obviously decrease the short-term pulmonary artery pressure, and improve di- aphragmatic muscle fatigue in OS patients.
出处
《郧阳医学院学报》
2008年第6期517-518,521,共3页
Journal of Yunyang Medical College
关键词
无创双水平正压通气
重叠综合征
膈肌疲劳
肺动脉压
Noninvasive Bi-level positive airway pressure ventilation
Overlap syndrome
Diaphragmatic muscle fatigue
Pulmonary artery pressure
