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急性心肌梗死(AMI)心肌细胞损伤标志物相关的临床研究 被引量:3

The clinical study of the relationship between cardiomyocyte injury markers and acute myocardial infarction
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摘要 目的研究心肌细胞损伤标志物与急性心肌梗死的关系。方法检测并分析急性心肌梗死(AMI)患者血清心肌细胞损伤标志物HS-CRP、SF、β2MG和cTnI水平改变。结果①AMI患者血清HS-CRP、SF、β2MG和cTnI水平较正常对照组明显增高,UAP患者血清HS-CRP、SF、β2MG和cTnI水平较正常对照组增高;②血清CTnI水平诊断AMI的特异性明显高于HS-CRP、SF、β2MG,AMI出现症状后9h血清cTnI诊断敏感性明显高于HS-CRP、SF和β2MG。结论AMI患者血清HS-CRP、SF、β2mg和cTnI水平升高,血清cTnI水平是AMI诊断和随访较好指标。 Objective To investigate the relationship between cardiomyoeyte injury markers and acute myocarclial infarction (AMI). Methods The serum level of HS-CRP, SF, β2MG and cTnI were detected and analysized in patients with AMI. Results ①The serum level of HS-CRP, SF, β2 MG and cTnI were significantly higher in patients with AMI than in control groups. The serum level of HS-CRP, SF, β2 MG and cTnI were significantly higher in patients with unstable angina pectoris (UAP) than in control groups. ② The specificity of serum cTnI was significantly higher than HS-CRP, SF and β2 MG in diagnosing AML The sensitivity of serum cTnI was significantly higher than HS-CRP, SF and β2 MG in patients who suffer from AMI over 9 hours. Conclusions The patients with AMI have high serum level of HS-CRP,SF,β2 MG and cTnⅠ. The serum level of cTnⅠ was a good marker in diagnosing or following patients with AMI.
作者 李龙 刘长江
出处 《中国现代药物应用》 2009年第2期3-4,共2页 Chinese Journal of Modern Drug Application
关键词 急性心肌梗死 心肌细胞损伤标志物 肌钙蛋白I Acute myocardial infarction Cardiomyocyte injury markers CTnⅠ
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