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不同剂量布吡卡因-芬太尼腰麻用于全宫切除术的临床观察

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摘要 目的探讨不同剂量布吡卡因伍用芬太尼腰麻用于全宫切除术的最小有效剂量,为临床提供最佳的药物剂量组合。方法将75例择期行全子宫切除术的病人,随机分为A、B、C三组,每组25例。A组腰麻用药为布吡卡因5mg与芬太尼20μg;B组布吡卡因7.5mg与芬太尼20pg;C组布吡卡因10mg与芬太尼20胆。观察三组用药后的MAP和HR变化、运动阻滞程度及平面消退时间。结果三组用药后的MAP均有不同程度的下降(P〈0.05),C组比A、B组下降更加显著(P〈0.01);A、B组间MAP变化无显著性差异(P〉0.05)。A、B两组分别有4、5例出现低血压需要用麻黄碱治疗,而C组有17例需用麻黄碱治疗以维持血压。C组Bromage评分集中在3~4分,而A、B两组大部分病例为2~3分;B、C组平面消退时间较A组明显延长(P〈0.01),但B、C组间比较无显著性差异(P〉0.05)。结论三组不同剂量的布吡卡因伍用20μg芬太尼行腰麻可实施全子宫切除术,而布吡卡因5.0mg及7.5mg对患者血液动力学影响小,副作用少,麻醉效果及肌松效果相当,但7.5mg维持时间较长,对估计可能手术难度较大或手术时间较长的患者更适用,值得临床推广。
作者 黄波
出处 《右江医学》 2008年第6期672-673,共2页 Chinese Youjiang Medical Journal
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