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子宫内膜异位症异位病灶神经分布的研究进展

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摘要 子宫内膜异位症(endometriosis,EMs)导致的疼痛症状长期以来一直困扰着患者和医生。近年来,对疼痛产生的机制进行了大量研究,包括遗传、炎症介质等方面,研究发现,子宫内膜异位症在位与异位内膜存在异常的神经分布,这些神经涉及感觉神经Aδ,感觉纤维C,胆碱能和肾上腺素能神经纤维等,并且常与增生的血管伴行。神经与血管能分泌疼痛介质及炎症因子,局部的炎症因子和疼痛介质亦可促进神经与血管的增生。神经纤维增生可能在子宫内膜异位症患者疼痛症状的产生及子宫内膜异位症的发病机制中起重要作用,异常的神经分布也可为子宫内膜异位症的诊断及治疗提供参考。
出处 《国际妇产科学杂志》 CAS 2008年第6期435-438,共4页 Journal of International Obstetrics and Gynecology
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