摘要
目的 探索利用颈，神经移位同时修复两根受损神经的可行性。方法建立大鼠颈，移位同时修复两根受损神经的动物模型，并与传统C7单组移位术进行神经再生疗效的比较。结果各项指标显示：术后早期（2～6周）颈，修复两根神经组神经再生效果劣于同时间段单组移位组，但随观察时间延长，术后8周起各项再生指标逐渐接近单组移位组和正常对照组，至12周，多数指标差异已无统计学意义。结论大鼠颈，神经根能提供足够再生纤维同时恢复两根受损神经功能。
Objective To test the feasibility of rescuing 2 impaired nerves by C7 nerve transfer （C7 nerve double-neurotization）. Methods Using adult male Sprague-Dawley rats（200 - 250 g）,a C7 nerve doubleneurotization model was established. At postoperative 2, 4, 6, 8, 12th weeks the recovery underwent musclenerve morphological, histological exarninations and was compared with C7 single neurotization. Results Most of the parameters in double neurotization group approximated to those in the single neurotization groups and normal control group at the end of observation period, thus indicating C7 nerve contains enough nerve fibers to provide sufficient regeneration for 2 recipient nerves. Conclusion Compared to single neurotization, C7 nerve double-neurotization has the advantage of restoring 2 nerve function at same time. This implicates its future clinical application in the treatment of severe brachial plexus avulsion injuries.
出处
《中华显微外科杂志》
CSCD
北大核心
2008年第6期420-423,共4页
Chinese Journal of Microsurgery
基金
上海市手外科临床医学中心基金
