摘要
目的探讨中晚期宫颈癌在介入化疗栓塞后病理改变及临床意义。方法20例中晚期宫颈癌患者选择经活检确诊为宫颈癌,临床分期Ⅱb-Ⅲa患者20例,进行介入治疗1-3次后观察其临床症状及癌灶的病理变化结果20例宫颈癌中15例Ⅱb期、5例Ⅲa期经1-2次术前介入化疗加栓塞,所有Ⅱb期患者及4例Ⅲa期最后均成功施行宫颈癌根治术,1例Ⅲa期因疗效不明显改行放射治疗。所有病例手术后标本后的病理切片中可见大量淋巴细胞浸润及坏死组织。结论中晚期宫颈癌术前介入化疗栓塞可缩小并软化宫颈局部癌灶,减少病灶的出血、改变肿瘤分期并顺利进行手术根治。
Objective Purpose To discuss pathological changes and clinical significance of advanced cervical carcinoma after interventional chemotherapy and embolization, Methods 20 patients in pathology proven cervical carcinoma and clinical staging over ⅡboClinical symptoms、tumor size and pathological changes were observed after interventional therapy 1-3 times. Results In 20cases, 15 cases of stage Ⅱb、5 cases of stage IIIa received interventional chemotherapy and embolization about one or two times. ALL of the cases of stage Ⅱb and 4 cases of stage Ilia received radical surgery of cervical carcinoma successfully, 1 case of stage Ⅲa received radiotherapy because of the not significant efficacy. Massive infiltration of lymphocytes and necrotic tissue were found in the slice from all of the surgical specimens. Conclusion Interventional chemotherapy and embolization before operation can shrink tumor size, softening the cervix cancer focus, decrease the hemorrhage, decrease the neoplasm staging and be helpful to sucessful radical surgery.
出处
《上海医学影像》
2008年第4期292-294,共3页
Shanghai Medical Imaging
关键词
宫颈癌
介入治疗
病理改变
Cervical cancer
Interventional therapy
Pathological changes
