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遗传性大肠癌的研究进展

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摘要 大肠癌是遗传背景最强、研究最深入的一种恶性肿瘤。它的发生发展是一个多步骤、多阶段、多基因参与的过程,是饮食、环境、遗传、疾病等多因素相互作用的结果。研究表明约三分之一大肠癌的发生与遗传相关。家族性腺瘤性息肉病(Familial adenomatous polyposis,FAP)和遗传性非息肉病性结直肠癌(Hereditary nonpolyposis colorectal cancer,HNPCC)是最常见的遗传性大肠癌,分别占所有大肠癌的1%和5%。
作者 袁瑛
出处 《医学新知》 CAS 2008年第6期311-314,F0004,共5页 New Medicine
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参考文献17

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